This study explores the idea, elements and systems of “green infrastructure” imbedded in the historical processes of urbanisation occurring in the Peruvian Andes region of Latin America. It addresses Ayacucho’s peripheral settlements in the catchment of the Cachi River, to highlight the vital roles of a multi-dimensional and multi-actors’ collaborative process under climate change and water scarcity in mountainous communities. Using “Urban Andes” project and the two international landscape design workshops (IUDW), the research integrates the traditional green infrastructure into newly proposed ones to articulate contemporary challenges. Taking into account the existing ancestral forms of social organisation for the self-provision of water infrastructure, three processes and design strategies of collaborative researches address various challenges at regional, urban and community scales. They display the diverse and complex systems of green infrastructure and underline the operation that took place between local and external stakeholders. Therefore, the situated and co-produced knowledge offers vital experience for future actors in the area and elsewhere.