Green space is important for urban resilience, as well as carbon reduction and carbon sinks. However, there is no effective approach to green space construction coping with climate change. Through a literature review of relative theories and practices, the paper proposes the synergic paradigm and design strategies of green space within the framework of Nature-based Solutions, including a dynamic adaptive paradigm and seven principle strategies. The paper uses a specific case as an empirical analysis to illustrate the paradigm and strategies. Suggestions and prospects of urban green space for climate adaptation are concluded ultimately. This paper develops the theories and methods of urban green space planning and design, which effectively support urban green space to respond to climate change.