Under the background of ecological civilization construction and green transformation, it has become a general trend to integrate the concept of ecological restoration into the landscape design of urban ecological space. To achieve the goal of ecological restoration, landscape ecological restoration should introduce evidence-based design concepts that can be measured objectively. The research focuses on the ecological restoration of urban waterfront space and constructs a four-dimensional conceptual framework based on evidence-based design. That is, water ecological measurement data analysis based on local factors, digital simulation of water ecological effects based on innovative technologies, design standards for water ecological engineering based on guiding requirements, and supply of water ecological system services based on multidisciplinary knowledge. Taking Sluice Gate Park on the South Bank of Jiaojiang River in Taizhou as an example, this study expounds how urban waterfront space design emphasizing ecological restoration can obtain a scientific, reasonable, and cost-effective design scheme through evidence-based methods, aiming to provide ideas and teaching and practical examples for other urban waterfront space ecological restoration.