The multiple health benefits brought by virtual green exposure have become a frontier hot topic in coupling virtual reality technology and health science, and there are a few hot topics and research progress in this field. This paper searched the literature in the core Web of Science database, and conducted clustering and co-occurrence analysis of the Keywords of related results through the visual analysis software Citespace. The results showed that exposure therapy has become one of the new therapies for treating depression due to its remarkable therapeutic effect, and exposure to a high-quality virtual green environment can have a lasting positive impact on both the body and mind. This paper mainly analyzes the promotion mechanism of a virtual green environment on mental health, the characteristics of the virtual green environment with a high promotion effect, and the recovery effect of VR-targeted intervention on depression from two aspects: mental health and physical health. With the maturity of VR technology and the popularization of digital medicine, future research should be combined with practice based on more theoretical achievements, focusing on the coupling mechanism between the two and the mental health promotion benefits of multi-sensory virtual green experience to enrich further and improve the theoretical system of virtual green exposure on depression recovery.